Introduction
Choosing the right clinical chemistry analyzer is important for lab performance, cost-efficiency, and accuracy. Beckman Coulter offers two popular options: the Beckman AU480 and the Beckman AU680. Both are powerful machines, but they are built for different types of labs.
In this article, we will compare the AU480 vs AU680 based on key features, throughput, applications, and lab needs. This will help you decide which one fits your clinical workflow best.
Overview of the Beckman AU480
The Beckman AU480 is designed for mid-volume laboratories. It is compact, reliable, and fits well in spaces where testing volume is moderate but consistent.
Key Features of AU480:
- Throughput: Up to 400 photometric tests/hour
- With ISE module: Up to 800 tests/hour
- Sample positions: 80 onboard
- Reagent positions: 63
- Footprint: Compact, benchtop design
- Ideal for: Small hospitals, diagnostic labs, satellite labs
This analyzer is known for its precision, ease of use, and smart automation features.
Overview of the Beckman AU680
The Beckman AU680 is a high-throughput analyzer. It suits large laboratories handling a wide range of tests daily.
Key Features of AU680:
- Throughput: Up to 800 photometric tests/hour
- With ISE module: Up to 1200 tests/hour
- Sample positions: 120 onboard
- Reagent positions: 80
- Footprint: Larger, floor-standing unit
- Ideal for: Large hospitals, reference labs, high-volume testing centers
The AU680 offers fast, continuous loading and excellent scalability.
Side-by-Side Feature Comparison
| Feature | Beckman AU480 | Beckman AU680 |
| Throughput | 400–800 tests/hour | 800–1200 tests/hour |
| Sample Positions | 80 | 120 |
| Reagent Positions | 63 | 80 |
| Dimensions | Compact benchtop | Larger floor unit |
| ISE Option | Yes | Yes |
| Target Lab Size | Mid-volume labs | High-volume labs |
| Integration Flexibility | Moderate | High |
| Maintenance Frequency | Standard | Slightly higher |
Which Analyzer Is Better for Your Lab?
Choose AU480 If:
- Your lab handles mid-range sample volumes
- You have space limitations
- You need a cost-effective solution
- Your staff is small and needs a user-friendly interface
- You’re running a hospital, specialty, or satellite lab
The AU480 is easy to install and operate, with less complex maintenance needs.
Choose AU680 If:
- Your lab processes large volumes daily
- You need a machine that supports continuous operation
- You want to expand testing capabilities in the future
- Your lab is part of a reference network or core hospital facility
The AU680 supports more samples, more reagents, and greater throughput—ideal for busy labs.
Performance & Throughput Comparison
The AU680’s higher speed comes into play when turnaround time is a priority. Labs performing thousands of tests per day will benefit more from AU680’s advanced automation.
The AU480, while slower, is optimized for labs that prioritize reliability and efficiency over bulk test volume.
Installation & Space Requirements
- AU480:
Can be installed on a lab bench. It fits well in tight spaces without compromising performance. - AU680:
Needs more floor space and proper power connections. It may require layout adjustments in the lab.
Cost Considerations
- AU480:
Lower acquisition cost, lower reagent usage, lower maintenance cost. - AU680:
Higher cost, but better suited for labs where high throughput offsets operational expenses.
Ease of Use & Maintenance
Both analyzers come with Beckman’s user-friendly software, automated maintenance features, and detailed system logs.
- AU480 has a faster learning curve.
- AU680 may require more frequent cleaning due to high usage, but it’s still designed for easy upkeep.
Flexibility & Lab Expansion
- AU480:
Great for stable environments with consistent test demand. Limited scalability. - AU680:
Designed for labs expecting growth. Compatible with lab automation and data management systems.
Application Areas
| Analyzer | Applications |
| AU480 | Routine chemistry, special chemistry, ISE testing |
| AU680 | High-throughput chemistry, large panels, batch testing, ISE testing |
Final Thoughts
Both Beckman AU480 and AU680 are excellent analyzers built to deliver reliable and accurate results. Your choice depends on your lab’s sample volume, budget, and space.
Go with AU480 if:
- You’re a mid-size lab
- Need a compact, affordable, and dependable system
Go with AU680 if:
- You’re a high-volume lab
- Require speed, scalability, and automation
No matter your choice, both analyzers support a wide range of tests and are backed by Beckman Coulter’s trusted service network.